Sight is precious, and every minute counts for Stargardt disease patients.
At Alkeus, we are on a mission to transform the treatment of Stargardt disease.
With our science, we are working to address the root cause of Stargardt disease for the very first time, and open new possibilities to treating a wide range of patients with degenerative eye disease.
We got here by forging a new path, by imagining a different way to develop a breakthrough precision medicine. Now we are poised to maximize the impact of our science by building a dynamic, patient-focused company.
Our mission is urgent, and our organization is growing rapidly to prepare for approval and launch. We are hiring for key roles across all functions.
Bringing gildeuretinol through approval and launch provides a potential lifeline to Stargardt patients and their families. For the Alkeus colleagues who make this happen, it will be a defining moment in their careers—and in their lives.
Join us and discover your future here.
Here are some of the specific positions we are hiring now:
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Vice President, Marketing
Manager: Chief Operating Officer
Position Location: Cambridge, MA
Work Arrangement: On-Site
About Alkeus Pharmaceuticals:
Alkeus Pharmaceuticals, Inc. is a late-stage biopharmaceutical company developing transformative therapeutics to address serious, progressive eye diseases that lead to blindness. Our lead compound, gildeuretinol (ALK-001), is an oral investigational drug being developed for the treatment of Stargardt disease and Geographic Atrophy (GA) secondary to dry age-related macular degeneration. For additional information, please visit our website at www.alkeuspharma.com.
Position Summary:
The Vice President of Marketing will be a key driver of our brand strategy, responsible for developing a brand plan and executing comprehensive marketing plans that align with our business objectives and resonate with our target audiences. This role requires a blend of strategic vision, hands-on execution, a deep understanding of biotech, rare and ophthalmology (Retina) specificities. The VP of Marketing will lead marketing strategies, collaborate closely with other departments to drive brand awareness, brand positioning, and product attribute communication.
Primary Responsibilities:
- Lead pre-commercialization marketing activities including brand planning and execution, patient identification and digital efforts
- Create a comprehensive marketing plan aligned with the company’s overall goals, including brand positioning, key messaging, and targeted audiences (patients, ECPs, caregivers, etc.)
- Partner with Medical Affairs and patient advocacy on ECP and patient educational initiatives
- Build relationships with KOLs, patient advocacy groups, and healthcare professionals
- Develop patient marketing strategies, plans and identified resources needed
- Develop brand positioning and marketing programs based on customer insights
- Partner with operational excellence and sales management teams
- Oversee the development and execution of multi-channel marketing campaigns across various platforms
- Understand and strictly apply US regulations and guidelines for marketing treatments for rare diseases. Contribute to an efficient and compliant medical and legal review process
- Partner with IT and agency to support gildeuretinol product launch
- Develop and manage the marketing budget, ensuring efficient allocation of resources
- Understand Stargardt genetic specificities to create relevant plans
- Partner with sales leadership to implement the brand strategy and develop impactful materials
- Establish clear objectives and key performance indicators (KPIs) to measure the success of marketing plan implementation
- Partner with legal and compliance to ensure the implementation of compliant messages and programs
Qualifications:
- Bachelor’s Degree required; MBA or another Advanced Degree preferred
- Minimum of 15 years of life sciences industry experience
- Extensive working knowledge of strategic and brand marketing and omni-channel approaches
- Prior collaboration with Key Opinion Leaders and investigators
- Visionary and innovative mindset with a passion for driving change and growth.
- Ability to thrive in a fast-paced, start-up environment with a hands-on approach.
- Proven track record of developing talent and being a culture champion
- Experience with key aspects of U.S. regulatory filings and launches
- Experience in competitive rare disease launch and commercialization in the U.S.
- Strong preference given to candidates with Retina/Ophthalmology.
Skills and Key Success Factors:
- Entrepreneurship spirit with a passion to build, learn and evolve with the team.
- Highly organized and detail oriented with a passion to deliver quality results.
- Demonstrated record of intellectual curiosity, innovation and creative problem solving with an entrepreneurial spirit
- Ability to lead fast-paced projects with a keen sense of urgency to get the job done well
- Evidence of “hands-on” experience and expertise
- Proven and successful track record as a team-player and collaborator in small working environments
- Highest levels of professionalism, confidence, personal values, and ethical standards
- Ability and aptitude to manage ambiguity and adaptability to change
- Emphasize the need for self-motivation and the ability to work independently
Other Relevant Information:
- Able to travel up to 30% of time
Alkeus Pharmaceuticals, Inc., is an equal opportunity employer and considers all qualified applicants for employment without regard to any characteristic protected by applicable law. We celebrate diversity and are committed to creating an inclusive environment for all employees. We encourage candidates of all backgrounds to apply.
To apply, please submit your resume to careers@alkeuspharma.com.
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Senior Director, Clinical Development
Manager: Chief Medical Officer
Position Location: Cambridge, MA
Work Arrangement: On-Site
About Alkeus Pharmaceuticals:
Alkeus Pharmaceuticals, Inc. is a late-stage biopharmaceutical company developing transformative therapeutics to address serious, progressive eye diseases that lead to blindness. Our lead compound, gildeuretinol (ALK-001), is an oral investigational drug being developed for the treatment of Stargardt disease and Geographic Atrophy (GA) secondary to dry age-related macular degeneration. For additional information, please visit our website at www.alkeuspharma.com.
Position Summary:
This role is instrumental in driving the successful development and launch of innovative therapies to address unmet medical needs. The Senior Director of Clinical Development will lead and oversee clinical development programs from early-stage trials through to regulatory approval, ensuring alignment with the company’s strategic objectives. The ideal candidate will bring experience in clinical trial design, execution, and regulatory interactions, with a particular focus on rare disease and small molecules.
Primary Responsibilities:
- Lead and mentor high-performing clinical development teams, fostering a culture of excellence and innovation
- Lead the design, implementation, and oversight of clinical development programs from Phase 1 to Pivotal studies
- Develop and manage clinical development strategies aligned with company goals and regulatory requirements
- Represent the company in interactions with regulatory agencies, including FDA, EMA, and PMDA
- Oversee the day-to-day medical monitoring of clinical trials, including patient eligibility assessments, protocol waivers, and safety parameter reviews
- Manage and coordinate with Clinical Research Organizations (CROs) throughout the clinical trial process
- Provide medical and scientific expertise to support clinical development activities
- Manage pharmacovigilance activities, including adverse event reporting and safety update reports
- Lead and mentor clinical development team members
- Contribute to the preparation of regulatory submissions, including INDs, NDAs, and other required documentation
- Collaborate with cross-functional teams to ensure alignment of clinical development plans with overall product strategy
Qualifications:
- MD or MD/PhD, with strong academic qualifications and board certification in Internal Medicine required
- Bachelor’s degree (preferably in science)
Preferred Qualifications:
- Ophthalmologist
Work Experience:
- 5+ years demonstrated clinical development experience in a pharmaceutical or biotechnology setting
- Knowledge of clinical development process and methods of scientific investigation, GCP, the FDA regulatory environment and guidelines, including study and protocol design
- Excellent working knowledge of FDA, EMA, PMDA regulations and expectations, Good Clinical Practice, ICH guidelines, and clinical drug development. Experience in representing the sponsor in front of regulatory agencies
- Demonstrate experience in clinical design and implementation of Phase 1 to Pivotal Clinical studies, with evidence direct leadership of trials that meet the timelines, budget, expected outcomes and lead to regulatory success of innovative medicines
- Sound medical/scientific writing skills and ability to analyze and interpret efficacy and safety data
- Direct experience in clinical development of small molecules
- Knowledge of statistical concepts as they relate to clinical plans
- Experience managing clinical CROs from RFP to statements of work to coordinating execution
- Knowledge of the day-to-day medical monitoring of clinical trials (e.g., responding to questions about patient eligibility and protocol waivers; review of safety parameters; receiving and processing SAEs, including the composition of SAE narratives; and IND expedited safety reports).
- Knowledge in pharmacovigilance, including the receipt and processing of ADRs, completion of MedWatch forms, and generation of Periodic Safety Update Reports
- Excellent problem solving, conflict resolution and team building
- Must demonstrate highly refined analytic and communication skills, and the ability to work effectively, both independently and in a team environment
Skills and Key Success Factors:
- Entrepreneurship spirit with a passion to build, learn and evolve with the team.
- Highly organized and detail oriented with a passion to deliver quality results.
- Demonstrated record of intellectual curiosity, innovation and creative problem solving with an entrepreneurial spirit.
- Ability to lead fast-paced projects with a keen sense of urgency to get the job done well
- Evidence of “hands-on” experience and expertise.
- Proven and successful track record as a team-player and collaborator in small working environments.
- Highest levels of professionalism, confidence, personal values, and ethical standards.
- Ability and aptitude to manage ambiguity and adaptability to change.
- Emphasize the need for self-motivation and the ability to work independently.
Other Relevant Information:
- Able to travel up to 25% of time
Alkeus Pharmaceuticals, Inc., is an equal opportunity employer and considers all qualified applicants for employment without regard to any characteristic protected by applicable law. We celebrate diversity and are committed to creating an inclusive environment for all employees. We encourage candidates of all backgrounds to apply.
To apply, please submit your resume to careers@alkeuspharma.com.
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Director of Strategic Planning
Manager: Chief Executive Officer
Position Location: Cambridge, MA
Work Arrangement: On-Site
About Alkeus Pharmaceuticals:
Alkeus Pharmaceuticals, Inc. is a late-stage biopharmaceutical company developing transformative therapeutics to address serious, progressive eye diseases that lead to blindness. Our lead compound, gildeuretinol (ALK-001), is an oral investigational drug being developed for the treatment of Stargardt disease and Geographic Atrophy (GA) secondary to dry age-related macular degeneration. For additional information, please visit our website at www.alkeuspharma.com.
Position Summary:
The Director of Strategic Planning is responsible for spearheading strategic planning for the company. Initiatives will include long range planning, corporate strategy development, and ad hoc initiatives to support Executive Leadership. This is a high-profile position which provides the opportunity to work with senior leadership across the organization to shape the strategic direction of a growing company.
Primary Responsibilities:
- Lead the development of the company’s long-range plan, effectively articulating the company’s long-term corporate vision, strategy, and pro-forma financial implications
- Interface with executive and functional leadership to facilitate selected corporate planning processes, such as quarterly business reviews and functional planning
- Works closely with all functions to include G&A, Clinical Development, Regulatory Affairs, Manufacturing, Quality and Commercial teams
- Lead/support ad hoc internal strategic initiatives, such as internal corporate strategy or operational workstreams for the executive leadership team and other internal stakeholders
- Prepare and deliver key corporate presentations (including corporate/portfolio presentations, board materials, etc.)
- Support portfolio strategy efforts which may include disease area planning, business development opportunity assessment, program assessment and valuation
- Assist in building and scaling company operations as the organization grows
Qualifications:
- Advanced degree preferred (i.e., MBA)
- Bachelor’s degree (preferably in science)
Work Experience:
- At least 8 years of relevant work experience, including 2-4 years in a strategic consulting role, either for a strategy consulting firm or in-house for a pharmaceutical company
- Strong knowledge of the pharmaceutical business including drug development and commercialization
- Preferred experience in startup biotech environments
- Strong strategic thinking and problem-solving skills, including ability to develop strategic frameworks to facilitate decision-making around complex opportunities
- Strong analytical & financial modeling skills (product forecasts, P&L, NPV models, etc.)
- Experience leading and motivating cross-functional teams, and ability to deliver on project timelines, progress, and outcomes
- Excellent communications skills, in writing and orally, including presentation to senior executives and board
- Strong technology skills, including proficiency with data visualization tools (e.g., Tableau, Power BI), familiarity with project management software and knowledge of industry-specific databases and information sources
Skills and Key Success Factors:
- Entrepreneurship spirit with a passion to build, learn and evolve with the team.
- Highly organized and detail oriented with a passion to deliver quality results.
- Demonstrated record of intellectual curiosity, innovation and creative problem solving with an entrepreneurial spirit.
- Ability to lead fast-paced projects with a keen sense of urgency to get the job done well
- Evidence of “hands-on” experience and expertise.
- Proven and successful track record as a team-player and collaborator in small working environments.
- Highest levels of professionalism, confidence, personal values, and ethical standards.
- Ability and aptitude to manage ambiguity and adaptability to change.
- Emphasize the need for self-motivation and the ability to work independently.
Other Relevant Information:
- Able to travel up to 25% of time
Alkeus Pharmaceuticals, Inc., is an equal opportunity employer and considers all qualified applicants for employment without regard to any characteristic protected by applicable law. We celebrate diversity and are committed to creating an inclusive environment for all employees. We encourage candidates of all backgrounds to apply.
To apply, please submit your resume to careers@alkeuspharma.com.
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General Interest
We are looking for enthusiastic professionals who want to be at the forefront of our mission and make a significant impact on the growth and direction of Alkeus Pharmaceuticals.
We invite you to apply and submit your resume to careers@alkeuspharma.com for general consideration.
Don’t see a role that’s a match?
Not all available roles are listed above and we are currently hiring across all functions. We have multiple roles available in medical affairs, regulatory, commercial, manufacturing, clinical, legal, financial, human resources, and business development.
If you think you’d be a fit for Alkeus, we’d love to hear from you at: